PHENOBARBITAL SODIUM MSDS - AN OVERVIEW

pentobarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Coadministration of CYP3A4 inducers may possibly lessen sufentanil amounts and efficacy, maybe precipitating withdrawal syndrome in individuals who definitely have developed physical dependence to sufentanil.